Fate might not be so unpredictable after all, TAU study suggests

Caption: Professor Joseph Klafter, Credit: AFTAU, Usage Restrictions: None

Why does it take so long for soul mates to find each other" How does disease spread through a person’s body" When will the next computer virus attack your hard-drive" A new theory published last month in Nature on the statistical concept of “First Passage Time,” or FPT, may provide the key to answering at least a few of these questions, says theory co-author Prof. Joseph Klafter from Tel Aviv University’s School of Chemistry. And the answers may lead to breakthroughs in medicine, mathematics, the environment, and elsewhere. Prof. Klafter and his colleagues from the University of Pierre & Marie Curie in Paris (where he has been visiting professor) are the first to have developed an analytical model that calculates the average arrival time – the mean FPT – of a randomly-moving object in a complex environment.

Understanding how randomly-moving objects arrive at a certain destination is no secret to scientists today. But no theory, until now, could predict the time it would take for an object to move between given addresses in a complex environment, like through the human body or the World Wide Web. Previous models only explained the passage of time when the event occurred in a homogenous environment, like in a vacuum or in a glass of water.

And in some instances, such as the movement of cancer cells in the human body, time is of the essence. The concept can best be understood by the question: How long will it take for a random walker to reach a certain destination"

Scientists from different backgrounds have studied and researched the predictability of FPT for decades. “Our new theory is exciting because it can be applied to a wide range of concepts in nature and mathematics,” explains Prof. Klafter, the Heinemann Chair of Physical Chemistry at Tel Aviv University. “It can be used by biologists, by ecologists, and even help computer scientists predict when the next big virus will hit their computer.”

When Prof. Klafter and his colleagues published their theory in Nature on November 1, they sparked interest from around the world – especially among biophysicists, who are looking for models to understand how long it takes for molecules to arrive at certain points in biological cells.

And although it will take months, maybe even years, for real-life experiments to prove the validity of this new theory, Prof. Klafter is looking forward to the results.

“I’ve received responses from researchers who are interested in using this model to analyze enzymes in cells,” says Prof. Klafter. “Enzymes are important for controlling functions in the body. If a biologist can estimate the FPT of a certain enzyme (at the place where this molecule reacts), then perhaps one could interfere with or manipulate the system to help prevent a disease or make a bodily function more efficient.”

He adds, “This theory can be applied to anything that moves randomly. It can be used for predicting when an enzyme will reach a target cell, how long a hungry animal will forage for food when food when is scarce – or even how viruses spread through the Internet.” ###

Prof. Klafter earned his Ph.D. at Tel Aviv University and completed post-doctoral work at MIT. Prior to joining the faculty at Tel Aviv University, he worked for Exxon. Prof. Klafter is the recipient of numerous awards and currently holds the position of chairman for the Academic Board at the Israel Science Foundation.

American Friends of Tel Aviv University supports Israel’s largest and most comprehensive center of higher learning. It is ranked among the world’s top 100 universities in science, biomedical studies, and social science, and rated one of the world’s top 200 universities overall. Internationally recognized for the scope and groundbreaking nature of its research programs, Tel Aviv University consistently produces work with profound implications for the future.

Contact: George Hunka ghunka@aftau.org 212-742-9070 American Friends of Tel Aviv University

Technorati Tags: First Passage Time and average arrival time or randomly-moving object or Freedom Calendar 12/08/07 - 12/15/07 and Kwanzaa Candle Lighting and Thermoelectric materials are 1 key to energy savings

Pearl Harbor Remembered

Audio: The audio is a Public Domain recording of the The Franklin D. Roosevelt Presidential Library and Museum Audio Archive From Wikipedia, the free encyclopedia

Images: All of The images in this collection are Public Domain. Credit, NAVAL HISTORICAL CENTER and Navy NewsStand - Eye on the Fleet.

Video: Flag videos are from YouTube - Broadcast Yourself courtesy users lilly7301 and gully42

For complete documentation of each image follow links below.

Navy NewsStand - Eye on the Fleet

071204-N-9758L-067 PEARL HARBOR, Hawaii (Dec. 6, 2007) Seaman Apprentice Chaz Chesnek, assigned to Naval Station (NAVSTA)

070911-N-4965F-001 PEARL HARBOR, Hawaii (Sept. 11, 2007) Pearl Harbor. U.S. Navy photo by Mass Communication Specialist 1st Class James E. Foehl (RELEASED)

NAVAL HISTORICAL CENTER

Pearl Harbor Raid, 7 December 1941;

Pearl Harbor in 1940-1941;

Japanese Forces in the Pearl Harbor Attack;

Overall Views of the Pearl Harbor Attack;

"Battleship Row" during the Pearl Harbor Attack;

Attacks off the West Side of Ford Island;

Attacks in the Navy Yard Area;

Attacks on Airfields and Aerial Combat;

Technorati Tags: Pear Harbor Remembered and Imperial Japanese Navy or aircraft carriers or Freedom Calendar 12/08/07 - 12/15/07 and Kwanzaa Candle Lighting and Thermoelectric materials are 1 key to energy savings

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